COBWEBS – Now in 3D!

In a recent Proceeding of the SPIE, Stacey demonstrated an extension of COBWEBS (Combined Online Bayesian Windowed Estimation of Background and Signal) to the third dimension. In simulated trajectories, this 3D variant of COBWEBS enables continuous tracking of freely diffusing objects in heterogeneous environments with background levels several fold larger than the actual signal. The extension to 3D is an important step towards an experimental implementation of COBWEBS, which will dramatically expand the scope of what is possible with active-feedback tracking.

Read the full paper here: Niver, A. J.; Welsher, K. D. Using COBWEBS for 3D active-feedback tracking of freely diffusing particles in tricky environments. Proc.SPIE 12386, 1238605, (2023).

See Stacey’s full talk from Photonics West on the Presentations tab or below: